functional foods. It was focused on anti-oxidative, anti-diabetic, anti-inflammatory, anti-obesity activities of 80%
ethanol extract from aerial parts of Angelica gigas (EEAG). We evaluate radical scavenging activity on DPPH and
ABTS radicals for anti-oxidative effect, inhibitory activity of α-amylase and α-glucosidase for anti-diabetic effect,
inhibitory activity on the production of nitric oxide in RAW 264.7 cell for anti-inflammatory effect, inhibitory
activity of lipase for anti-obesity effect. IC50 of DPPH radical scavenging activity was 278.68 μg/mL and ABTS
radical scavenging activity was 3,920.00 μg/mL. The inhibitory activity of α-amylase was 89.07% (1,000 μg/mL) and
IC50 of α-amylase inhibitory activity was 452.16 μg/mL. The EEAG(10,000 μg/mL) showed 10.55% lower pancreatic
lipase inhibition activity. The NO product level of EEAG (100 μg/mL) was 2.2 μM, EEAG (100 μg/mL) showed
strongly decrease in NO production compared with the only LPS treatment. These results suggest that the aerial parts
of Angelica gigas Nakai may be useful for functional materials such as anti-oxidative, anti-diabetic, anti-inflammatory
agent.
3-김희연지상부(최종).pdf
